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Public Health Genomics and Precision Health Knowledge Base (v9.0)
PHGKB
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Public Health Genomics Branch
PHGKB Weekly Horizon Scan
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Precision Health Database
Precision Health Database|Search|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
Last data update: Apr 30, 2024
. (Total: 63724 Documents since 2012)
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A Communication and Decision-Making Framework for Pediatric Precision Medicine.
Brittany L Greene et al. Pediatrics 2024
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Polygenic risk scores, radiation treatment exposures and subsequent cancer risk in childhood cancer survivors.
Todd M Gibson et al. Nat Med 2024
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Health-Related quality of life and DNA Methylation-Based aging biomarkers among survivors of childhood cancer.
Noel-Marie Plonski et al. J Natl Cancer Inst 2024
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The psychological impact of genetic testing in childhood cancer: A systematic review.
Sophie Van Hoyweghen et al. Psychooncology 2024 33(1) e6279
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Clinical trio genome sequencing facilitates the interpretation of variants in cancer predisposition genes in paediatric tumour patients
C. Shroeder et al, EJHG, July 28, 2023
Parents' expectations, preferences, and recall of germline findings in a childhood cancer precision medicine trial.
Brittany C McGill et al. Cancer 2023
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Parents' and adolescents' perspectives and understanding of information about childhood cancer precision medicine.
Jessica M Gereis et al. Cancer 2023
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Precision Medicine Is Changing the Roles of Healthcare Professionals, Scientists, and Research Staff: Learnings from a Childhood Cancer Precision Medicine Trial
R Daly et al, JPM, June 23, 2023
Protocol for a comprehensive prospective cohort study of trio-based whole-genome sequencing for underlying cancer predisposition in paediatric and adolescent patients newly diagnosed with cancer: the PREDICT study.
Noemi Auxiliadora Fuentes Bolanos et al. BMJ Open 2023 13(5) e070082
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A clinical screening tool to detect genetic cancer predisposition in pediatric oncology shows high sensitivity but can miss a substantial percentage of affected children.
Ulrike Anne Friedrich et al. Genet Med 2023 100875
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Longitudinal Analysis of Cancer Risk in Children and Adults With Germline PTEN Variants.
Lamis Yehia et al. JAMA Netw Open 6(4) e239705
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Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication
Y Liu et al, Nat Comm, April 5, 2023
Diagnostic classification of childhood cancer using multiscale transcriptomics.
Federico Comitani et al. Nature medicine 2023
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Supratentorial CNS-PNETs in children; a Swedish population-based study with molecular re-evaluation and long-term follow-up.
Elizabeth Schepke et al. Clinical epigenetics 2023 15(1) 40
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Germline pathogenic variants in 786 neuroblastoma patients.
Jung Kim et al. medRxiv : the preprint server for health sciences 2023
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Assessment of Cancer Predisposition Syndromes in a National Cohort of Children With a Neoplasm.
Jette J Bakhuizen et al. JAMA network open 2023 6(2) e2254157
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Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response.
Lee Shawn H R et al. Nature medicine 2023
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Association of Inherited Genetic Factors With Drug-Induced Hepatic Damage Among Children With Acute Lymphoblastic Leukemia.
Yang Wenjian et al. JAMA network open 2022 5(12) e2248803
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Delphi Panel Consensus Recommendations for Screening and Managing Childhood Cancer Survivors at Risk for Cardiomyopathy.
Aziz-Bose Rahela et al. JACC. CardioOncology 2022 4(3) 354-367
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Pharmacogenomics in Children.
Rieder Michael J et al. Methods in molecular biology (Clifton, N.J.) 2022 2547569-593
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What's in a Name? Parents' and Healthcare Professionals' Preferred Terminology for Pathogenic Variants in Childhood Cancer Predisposition Genes.
Hunter Jacqueline D et al. Journal of personalized medicine 2022 12(8)
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Heterozygous BRCA1/2 and Mismatch Repair Gene Pathogenic Variants in Children and Adolescents with Cancer.
Kratz Christian P et al. Journal of the National Cancer Institute 2022
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Predicting chronic morbidity in childhood cancer survivors.
Vrooman Lynda M et al. Nature medicine 2022
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Genetic risk score enhances the risk prediction of severe obesity in adult survivors of childhood cancer.
Sapkota Yadav et al. Nature medicine 2022
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Technical Validation and Clinical Utility of an NGS Targeted Panel to Improve Molecular Characterization of Pediatric Acute Leukemia.
Vicente-Garcés Clara et al. Frontiers in molecular biosciences 2022 9854098
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Genome-wide association studies identify novel genetic loci for epigenetic age acceleration among survivors of childhood cancer
Q Dong et al, Genome Medicine, March 22, 2022
Parents', Health Care Professionals', and Scientists' Experiences of a Precision Medicine Pilot Trial for Patients With High-Risk Childhood Cancer: A Qualitative Study.
Vetsch Janine et al. JCO precision oncology 2022 31-11
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Cohort-based association study of germline genetic variants with acute and chronic health complications of childhood cancer and its treatment: Genetic Risks for Childhood Cancer Complications Switzerland (GECCOS) study protocol.
Waespe Nicolas et al. BMJ open 2022 12(1) e052131
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Clinical and economic impact of molecular testing for BRAF fusion in pediatric low-grade Glioma.
Rios Juan David et al. BMC pediatrics 2022 22(1) 13
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Clinical Value of NGS Genomic Studies for Clinical Management of Pediatric and Young Adult Bone Sarcomas.
Gutiérrez-Jimeno Miriam et al. Cancers 2021 13(21)
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Page last reviewed:
Feb 1, 2024
Page last updated:
Apr 30, 2024
Content source:
Public Health Genomics Branch in the Division of Blood Disorders and Public Health Genomics
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National Center on Birth Defects and Developmental Disabilities
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